Bavachalcone

• CAT Number: I002968
• CAS Number: 28448-85-3
• Molecular Formula: C20H20O4
• Molecular Weight: 324.37
• Purity: ≥95%
• Target: Bacterial; Antibiotic
• Solubility: DMSO: ≥ 34 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (E)-1-[2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
• InChI: InChI=1S/C20H20O4/c1-13(2)3-7-15-11-17(20(24)12-19(15)23)18(22)10-6-14-4-8-16(21)9-5-14/h3-6,8-12,21,23-24H,7H2,1-2H3/b10-6+
• InChIKey: BLZGPHNVMRXDCB-UXBLZVDNSA-N
• SMILES: CC(=CCC1=CC(=C(C=C1O)O)C(=O)/C=C/C2=CC=C(C=C2)O)C

Bavachalcone（Cat No.:I002968）is a naturally occurring chalcone extracted from the seeds of Psoralea corylifolia, a plant used in traditional medicine. It possesses various pharmacological properties, including antioxidant, anti-inflammatory, and antimicrobial effects. Bavachalcone has shown potential in cancer research due to its ability to inhibit cancer cell proliferation and induce apoptosis. Additionally, it has demonstrated activity against skin conditions and immune modulation. With its bioactive effects, bavachalcone is increasingly studied as a candidate for therapeutic applications, especially in skin health, immune support, and cancer treatment research.

Reference

[1]. Park CK, et al. Bavachalcone inhibits osteoclast differentiation through suppression of NFATc1 induction by RANKL. Biochem Pharmacol. 2008 Jun 1;75(11):2175-82.
[2]. Choi YH, et al. In vitro BACE-1 inhibitory phenolic components from the seeds of Psoralea corylifolia. Planta Med. 2008 Sep;74(11):1405-8.
[3]. Shan L, et al. Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases. Evid Based Complement Alternat Med. 2014;2014:958937.