For research use only. Not for therapeutic Use.
Bavisant, also known as JNJ-31001074, is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. Histamine H3 receptors reside on
| Catalog Number | I003958 |
| CAS Number | 929622-08-2(free base) |
| Synonyms | JNJ-31001074; JNJ31001074; JNJ 31001074; Bavisant.;(4-cyclopropylpiperazin-1-yl)(4-(morpholinomethyl)phenyl)methanone |
| Molecular Formula | C19H27N3O2 |
| Purity | ≥95% |
| Target | H3 receptor antagonist |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| InChI | 1S/C19H27N3O2/c23-19(22-9-7-21(8-10-22)18-5-6-18)17-3-1-16(2-4-17)15-20-11-13-24-14-12-20/h1-4,18H,5-15H2 |
| InChIKey | BGBVSGSIXIIREO-UHFFFAOYSA-N |
| SMILES | O=C(N1CCN(C2CC2)CC1)C3=CC=C(CN4CCOCC4)C=C3 |
| Reference | </br>1: Weisler RH, Pandina GJ, Daly EJ, Cooper K, Gassmann-Mayer C; 31001074-ATT2001 </br> Study Investigators. Randomized clinical study of a histamine H3 receptor</br> antagonist for the treatment of adults with attention-deficit |
