BAY-179

• CAT Number: I044005
• CAS Number: 2764880-87-5
• Molecular Formula: C23H21N5OS
• Molecular Weight: 415.51
• Purity: ≥95%
• Synonyms: 4-(1-benzofuran-2-yl)-2-[1-(1H-imidazo[4,5-b]pyridin-2-ylmethyl)piperidin-4-yl]-1,3-thiazole
• InChI: InChI=1S/C23H21N5OS/c1-2-6-19-16(4-1)12-20(29-19)18-14-30-23(26-18)15-7-10-28(11-8-15)13-21-25-17-5-3-9-24-22(17)27-21/h1-6,9,12,14-15H,7-8,10-11,13H2,(H,24,25,27)
• InChIKey: JOCPQSJABURDDD-UHFFFAOYSA-N
• SMILES: C1CN(CCC1C2=NC(=CS2)C3=CC4=CC=CC=C4O3)CC5=NC6=C(N5)C=CC=N6

BAY-179 is a potent, selective, and species cross-reactive complex I inhibitor (IC50=79 µM)[1].

Reference

[1]. Mowat J, et al. Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179. ACS Med Chem Lett. 2022;13(3):348-357. Published 2022 Feb 18.
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