For research use only. Not for therapeutic Use.
BAY-1797(CAT: I017383) is a potent, orally active, and selective antagonist of the P2X4 receptor, with an IC50 of 211 nM against human P2X4. By targeting P2X4, a ligand-gated ion channel involved in pain signaling, inflammation, and neuropathic conditions, BAY-1797 offers a valuable tool for exploring the role of P2X4 in various physiological and pathological processes. It is particularly significant in neurological and pain research, where it aids in investigating therapeutic strategies for conditions such as neuropathic pain, inflammation, and cardiovascular diseases. The oral bioavailability and selectivity of BAY-1797 make it a promising compound for preclinical and clinical studies.
| Catalog Number | I017383 |
| CAS Number | 2055602-83-8 |
| Molecular Formula | C₂₀H₁₇ClN₂O₄S |
| Purity | ≥95% |
| Target | P2X Receptor |
| IUPAC Name | N-[4-(3-chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide |
| InChI | InChI=1S/C20H17ClN2O4S/c21-15-7-4-8-17(12-15)27-18-10-9-16(13-19(18)28(22,25)26)23-20(24)11-14-5-2-1-3-6-14/h1-10,12-13H,11H2,(H,23,24)(H2,22,25,26) |
| InChIKey | CSJYMAFXYMYNCK-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CC(=O)NC2=CC(=C(C=C2)OC3=CC(=CC=C3)Cl)S(=O)(=O)N |
