For research use only. Not for therapeutic Use.
BAY 1892005 is a regulator of p53 protein and acts on p53 condensates without causing mutant p53 reactivation[1].
BAY 1892005 inhibits cell proliferation in p53 mutated cell lines Huh7 (IC50=11.2 μM) and H358 (IC50=11.1 μM)[1].
| Catalog Number | I040524 |
| CAS Number | 2036352-13-1 |
| Synonyms | 2-chloro-N-[4-(2-fluorophenyl)-1,3-thiazol-2-yl]acetamide |
| Molecular Formula | C11H8ClFN2OS |
| Purity | ≥95% |
| InChI | InChI=1S/C11H8ClFN2OS/c12-5-10(16)15-11-14-9(6-17-11)7-3-1-2-4-8(7)13/h1-4,6H,5H2,(H,14,15,16) |
| InChIKey | JYANOVDYYBXVNL-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)C2=CSC(=N2)NC(=O)CCl)F |
| Reference | [1]. Lemos C, et al. Identification of Small Molecules that Modulate Mutant p53 Condensation[J].iScience, 2020, 23(9):101517. |
