For research use only. Not for therapeutic Use.
BAY-728 can be used as a negative control of BAY-805. BAY-805 is a potent and selective Inhibitor of USP21[1].
| Catalog Number | I041406 |
| Synonyms | N-[(2S)-1-[[5-[(4-cyanophenyl)methyl]-1,3,4-thiadiazol-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-(trifluoromethyl)cyclohexane-1-carboxamide |
| Molecular Formula | C24H28F3N5O2S |
| Purity | ≥95% |
| InChI | InChI=1S/C24H28F3N5O2S/c1-15(2)12-18(29-21(34)23(24(25,26)27)10-4-3-5-11-23)20(33)30-22-32-31-19(35-22)13-16-6-8-17(14-28)9-7-16/h6-9,15,18H,3-5,10-13H2,1-2H3,(H,29,34)(H,30,32,33)/t18-/m0/s1 |
| InChIKey | LXRBPWHQMGKMRT-SFHVURJKSA-N |
| SMILES | CC(C)CC(C(=O)NC1=NN=C(S1)CC2=CC=C(C=C2)C#N)NC(=O)C3(CCCCC3)C(F)(F)F |
| Reference | [1]. Göricke F, et al. Discovery and Characterization of BAY-805, a Potent and Selective Inhibitor of Ubiquitin-Specific Protease USP21. J Med Chem. 2023 Feb 20. |
