BAY-8002

• CAT Number: I019309
• CAS Number: 724440-27-1
• Molecular Formula: C₂₀H₁₄ClNO₅S
• Molecular Weight: 415.85
• Purity: ≥95%
• Target: Monocarboxylate Transporter

BAY-8002(CAT: I019309) is a potent, selective, and orally active inhibitor of monocarboxylate transporter 1 (MCT1). MCT1 is a transporter protein involved in the transport of monocarboxylates, such as lactate and pyruvate, across cell membranes. By inhibiting MCT1, BAY-8002 can disrupt the transportation of monocarboxylates, potentially affecting various physiological processes that rely on the transport of these molecules.

Reference

[1]. Quanz M, et al. Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance. Mol Cancer Ther. 2018 Nov;17(11):2285-2296.