BBMP

• CAT Number: I023041
• CAS Number: 97120-13-3
• Molecular Formula: C12H11BrN2O3S
• Molecular Weight: 343.20
• Purity: 98%
• Synonyms: BBMP
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 5-Benzylsulfonyl-4-bromo-2-methylpyridazin-3-one
• InChI: InChI=1S/C12H11BrN2O3S/c1-15-12(16)11(13)10(7-14-15)19(17,18)8-9-5-3-2-4-6-9/h2-7H,8H2,1H3
• InChIKey: ICJYBAMRYLSLQT-UHFFFAOYSA-N
• SMILES: O=C1C(Br)=C(S(=O)(CC2=CC=CC=C2)=O)C=NN1C

BBMP(CAT: I023041) is a selective inhibitor of the mitochondrial permeability transition pore (PTP), a critical regulator of mitochondrial membrane potential and cell survival. By preventing the opening of the PTP, BBMP protects against mitochondrial dysfunction and subsequent apoptosis or necrosis. This compound is particularly valuable in mitochondrial research, supporting studies on ischemia-reperfusion injury, neurodegeneration, and other conditions associated with mitochondrial damage. BBMP is an essential tool for exploring the role of PTP in cellular physiology and pathology, aiding the development of therapies targeting mitochondrial dysfunction in diseases such as cardiovascular disorders and neurodegenerative conditions.