For research use only. Not for therapeutic Use.
BCH001（Cat No.:I023056）is a small molecule compound being investigated for its potential as a therapeutic agent in oncology and other diseases. It is designed to inhibit specific molecular targets involved in cell proliferation, survival, and resistance mechanisms in cancer cells. Preclinical studies suggest that BCH001 may have activity against various cancer types, including those with resistance to conventional therapies. The compound is also being explored for its potential effects on immune modulation and its ability to enhance the efficacy of existing cancer treatments. Further clinical trials are needed to evaluate its safety, efficacy, and broader therapeutic potential.
| Catalog Number | I023056 |
| CAS Number | 384859-58-9 |
| Synonyms | BCH001; BCH 001; BCH-001; |
| Molecular Formula | C20H15F3N2O5 |
| Purity | 98% |
| Target | DNA/RNA Synthesis |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2-[[3-ethoxycarbonyl-6-(trifluoromethoxy)quinolin-4-yl]amino]benzoic acid |
| InChI | InChI=1S/C20H15F3N2O5/c1-2-29-19(28)14-10-24-15-8-7-11(30-20(21,22)23)9-13(15)17(14)25-16-6-4-3-5-12(16)18(26)27/h3-10H,2H2,1H3,(H,24,25)(H,26,27) |
| InChIKey | FWJMVZAVAUGMDX-UHFFFAOYSA-N |
| SMILES | CCOC(=O)C1=CN=C2C=CC(=CC2=C1NC3=CC=CC=C3C(=O)O)OC(F)(F)F |
| Reference | 1: Nagpal N, Wang J, Zeng J, Lo E, Moon DH, Luk K, Braun RO, Burroughs LM, Keel SB, Reilly C, Lindsley RC, Wolfe SA, Tai AK, Cahan P, Bauer DE, Fong YW, Agarwal S. Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells. Cell Stem Cell. 2020 Jun 4;26(6):896-909.e8. doi: 10.1016/j.stem.2020.03.016. Epub 2020 Apr 21. PMID: 32320679; PMCID: PMC7275922. |
