BCL6-IN-5

• CAT Number: I045746
• CAS Number: 2253878-09-8
• Molecular Formula: C17H19Cl2N5O2
• Molecular Weight: 396.27
• Purity: ≥95%
• Synonyms: 5-[(2,5-dichloropyrimidin-4-yl)amino]-3-(3-hydroxy-3-methylbutyl)-1-methylbenzimidazol-2-one
• InChI: InChI=1S/C17H19Cl2N5O2/c1-17(2,26)6-7-24-13-8-10(4-5-12(13)23(3)16(24)25)21-14-11(18)9-20-15(19)22-14/h4-5,8-9,26H,6-7H2,1-3H3,(H,20,21,22)
• InChIKey: NKMQWLPBEJJYCN-UHFFFAOYSA-N
• SMILES: CC(C)(CCN1C2=C(C=CC(=C2)NC3=NC(=NC=C3Cl)Cl)N(C1=O)C)O

BCL6-IN-5 is a potent BCL6 inhibitor exacted from patent WO2018215801A1, example 1n, has a pIC50 of 5.82[1].

Reference

[1]. Benjamin Richard BELLENIE, et al. Benzimidazolone derived inhibitors of bcl6. WO2018215801A1.