Beaucage reagent

• CAT Number: I004494
• CAS Number: 66304-01-6
• Molecular Formula: C7H4O3S2
• Molecular Weight: 200.23
• Purity: ≥95%
• Target: DNA/RNA Synthesis
• Solubility: 10 mM in DMSO
• Storage: Store at -20C

Beaucage reagent（Cat No.:I004494） is a potent compound known for its ability to induce DNA cleavage. It is commonly used in synthetic chemistry and molecular biology to facilitate the synthesis of modified DNA or RNA molecules. Beaucage reagent, specifically the 2-cyanoethyl-N, N-diisopropylchlorophosphoramidite derivative, can selectively cleave the internucleotide phosphodiester bond, leading to the fragmentation of DNA strands. This property allows for controlled modifications and manipulations of DNA sequences, making Beaucage reagent a valuable tool in various research applications, such as oligonucleotide synthesis and DNA sequencing.

Reference

[1]. Zheng J, et al. Thiol-dependent DNA cleavage by aminomethylated Beaucage/’s reagent. Org Biomol Chem. 2010 Mar 21;8(6):1293-5.