Beclomethasone-d5

• CAT Number: S000839
• CAS Number: 1263143-48-1
• Molecular Formula: C22H24D5ClO5
• Molecular Weight: 413.95
• Purity: ≥95%
• IUPAC Name: (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-4,6,6-trideuterio-17-(2,2-dideuterio-2-hydroxyacetyl)-11,17-dihydroxy-10,13,16-trimethyl-8,11,12,14,15,16-hexahydro-7H-cyclopenta[a]phenanthren-3-one
• InChI: InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1/i4D2,9D,11D2
• InChIKey: NBMKJKDGKREAPL-PAEDUFRWSA-N
• SMILES: [2H]C1=C2[C@](C=CC1=O)([C@]3([C@H](C[C@]4([C@H]([C@@H]3CC2([2H])[2H])C[C@@H]([C@@]4(C(=O)C([2H])([2H])O)O)C)C)O)Cl)C

Beclomethasone-d5 is a high-purity, deuterium-labeled analog of Beclomethasone, a corticosteroid extensively used in pharmaceutical research. This compound, featuring five deuterium atoms, is crucial for studying drug metabolism, pharmacokinetics, and pharmacodynamics. The incorporation of stable heavy isotopes like deuterium enhances the precision and reliability of analytical results. Beclomethasone-d5 is ideal for clinical research and drug development, offering insights into the pharmacokinetic and metabolic profiles of corticosteroids. Its stable isotope labeling ensures consistent and reproducible data, making it a valuable tool for developing more effective and safer therapeutic agents. This compound integrates seamlessly into existing experimental protocols, providing a robust solution for high-precision scientific investigations.