For research use only. Not for therapeutic Use.
Beclometasone dipropionate (INN modified) or beclomethasone dipropionate (USAN, former BAN), also referred to as beclometasone (INN), is a potent glucocorticoid steroid. In the form of an inhaler (e.g. Clenil, Qvar), a wide number of brands of which are available, it is used for the prophylaxis of asthma. As a nasal spray (e.g. Beconase, alanase, Vancenase), it is used for the treatment of rhinitis (e.g. hayfever) and sinusitis. In some instances it is used by oral pathologists in the treatment of unusually severe aphthous ulcers.
| Catalog Number | A000353 |
| CAS Number | 5534-09-8 |
| Synonyms | Beclometasone dipropionate; Beconase; Beclovent; Vancenase; Beclazone |
| Molecular Formula | C28H37ClO7 |
| Purity | ≥95% |
| Target | Vitamin D Related/Nuclear Receptor |
| Solubility | >17mg/mL in DMSO |
| Storage | -20°C |
| InChI | 1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 |
| InChIKey | KUVIULQEHSCUHY-XYWKZLDCSA-N |
| SMILES | CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)Cl)O)C)C)OC(=O)CC |
| Reference | 1: Singh D, Corradi M, Spinola M, Papi A, Usmani OS, Scuri M, Petruzzelli S, 2: Small CJ, Gillespie M. Pharmacokinetics of Beclomethasone Dipropionate 3: Hampel FC Jr, Carr W, Gillespie M, Small CJ. Evaluation of beclomethasone <br> <br> 6: Triolo D, Craparo EF, Porsio B, Fiorica C, Giammona G, Cavallaro G. Polymeric <br> 8: Lee YJ, Cheon JH, Kim JH, Yoo S, Lee HJ, Park SJ, Hong SP, Kim TI, Kim WH. 9: Manguso F, Bennato R, Lombardi G, Riccio E, Costantino G, Fries W. Efficacy <br> |
