For research use only. Not for therapeutic Use.
Beclomethasone Hemisuccinate (Cat No.:C001091) is a synthetic corticosteroid used as an anti-inflammatory and immunosuppressive agent. It is a derivative of beclomethasone, a glucocorticoid medication used for various respiratory conditions, including asthma and allergic rhinitis. The hemisuccinate form enhances its water solubility for certain applications. Beclomethasone Hemisuccinate may be used in pharmaceutical formulations, particularly in inhalation therapies and nasal sprays. Its specific properties and uses make it valuable in medical research and drug development.
| Catalog Number | C001091 |
| CAS Number | 75899-57-9 |
| Synonyms | (11β,16β)-21-(3-Carboxy-1-oxopropoxy)-9-chloro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione |
| Molecular Formula | C₂₆H₃₃ClO₈ |
| Purity | ≥95% |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Pale Beige to Pale Brown Solid |
| Storage | -20°C, Hygroscopic |
| IUPAC Name | 4-[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid |
| InChI | InChI=1S/C26H33ClO8/c1-14-10-18-17-5-4-15-11-16(28)8-9-23(15,2)25(17,27)19(29)12-24(18,3)26(14,34)20(30)13-35-22(33)7-6-21(31)32/h8-9,11,14,17-19,29,34H,4-7,10,12-13H2,1-3H3,(H,31,32)/t14-,17-,18-,19-,23-,24-,25-,26-/m0/s1 |
| InChIKey | PEPQYWLBRHFUAQ-UYXSPTSISA-N |
| SMILES | CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)CCC(=O)O)O)C)O)Cl)C |
| Reference | Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982); Rao, M., et al.: J. Asthma, 19, 21 (1982); Small, P., et al.: Ann. Allergy, 49, 127 (1982); Brogden, R.N., et al.: Drugs, 28, 99 (1984) |
