For research use only. Not for therapeutic Use.
Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities[1][2][3]. Bellidifolin also acts as a viral protein R (Vpr) inhibitor[4].
| Catalog Number | R066029 |
| CAS Number | 2798-25-6 |
| Synonyms | 1,5,8-trihydroxy-3-methoxyxanthen-9-one |
| Molecular Formula | C14H10O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H10O6/c1-19-6-4-9(17)11-10(5-6)20-14-8(16)3-2-7(15)12(14)13(11)18/h2-5,15-17H,1H3 |
| InChIKey | JDIORNFCMMYMLF-UHFFFAOYSA-N |
| SMILES | COC1=CC(=C2C(=C1)OC3=C(C=CC(=C3C2=O)O)O)O |
| Reference | [1]. Zhao ZY, et al. Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms. J Toxicol Environ Health A. 2017;80(22):1187-1192. [2]. Zheng XY, et al. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153(3):854-63. [3]. Basnet P, et al. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60(6):507-11. [4]. Woo SY, et al. Viral protein R inhibitors from Swertia chirata of Myanmar. J Biosci Bioeng. 2019 May 7. |
