For research use only. Not for therapeutic Use.
Beloxepin(CAT: I004135) is a selective and potent antagonist of the histamine H1 receptor, primarily investigated for its anti-allergic and anti-inflammatory properties. By inhibiting H1 receptor activity, Beloxepin mitigates histamine-induced physiological responses such as vasodilation, edema, and bronchoconstriction. This compound is of significant interest in the research of allergic conditions, including rhinitis, urticaria, and asthma. Its high receptor specificity and efficacy make it a valuable tool for studying histamine-mediated pathways and developing targeted therapies for allergic and inflammatory disorders.
| Catalog Number | I004135 |
| CAS Number | 135928-30-2 |
| Synonyms | ADL-6906; ADL 6906; ADL6906; ORG-4428; ORG4428; ORG 4428; Beloxepin.;cis-1,3,4,13b-Tetrahydro-2,10-dimethyldibenz(2,3:6,7)oxepino(4,5-c)pyridin-4a(2H)-ol |
| Molecular Formula | C19H21NO2 |
| Purity | ≥95% |
| Target | norepinephrine uptake inhibitor |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| IUPAC Name | (2R,7R)-4,16-dimethyl-14-oxa-4-azatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-7-ol |
| InChI | InChI=1S/C19H21NO2/c1-13-6-5-7-14-16-12-20(2)11-10-19(16,21)15-8-3-4-9-17(15)22-18(13)14/h3-9,16,21H,10-12H2,1-2H3/t16-,19-/m0/s1 |
| InChIKey | RPMDQAYGQBREBS-LPHOPBHVSA-N |
| SMILES | CC1=CC=CC2=C1OC3=CC=CC=C3C4(C2CN(CC4)C)O |
