Bendamustine-d6 (major) D-Mannitol Ester

• CAT Number: R064188
• CAS Number: NA
• Molecular Formula: C₂₂H₂₈D₆Cl₂N₃O₇
• Molecular Weight: 529.46
• Purity: ≥95%
• Synonyms: (2R,3R,4R,5R)-2,3,4,5,6-Pentahydroxyhexyl 4-(5-(bis(2-Chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate-d6 (major)
• Storage: Store at +4°C

Bendamustine-d6 D-Mannitol Ester is a deuterated derivative of bendamustine, where six hydrogen atoms are replaced with deuterium and it is esterified with D-mannitol. This isotopically labeled compound is used in pharmaceutical research, particularly in the study of the pharmacokinetics, metabolism, and drug delivery mechanisms of bendamustine, a chemotherapy drug used to treat certain types of cancer. The deuterium labeling allows for precise tracking in mass spectrometry, aiding researchers in understanding the metabolic pathways and interactions of bendamustine in biological systems. The esterification with D-mannitol may enhance the solubility and stability of the compound, making it useful in various experimental conditions. This compound is crucial for optimizing bendamustine-based therapies, contributing to the development of more effective cancer treatments with potentially reduced side effects.