Benserazide HCl

• CAT Number: A001206
• CAS Number: 14919-77-8
• Molecular Formula: C10H15N3O5 • HCl
• Molecular Weight: 293.70
• Purity: ≥95%
• Synonyms: Ro-4-4602
• Target: aromatic-L-amino-acid decarboxylase
• Storage: 3 years -20C powder
• IUPAC Name: 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride
• InChI: InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H
• InChIKey: ULFCBIUXQQYDEI-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl

Benserazide HCl（Cat No.:A001206）is a peripheral dopa decarboxylase inhibitor used in combination with levodopa for treating Parkinson’s disease. By inhibiting the enzyme that converts levodopa to dopamine outside the brain, benserazide ensures more levodopa reaches the brain, where it can be converted to dopamine, thereby enhancing the drug’s effectiveness in managing motor symptoms. This approach minimizes peripheral side effects, such as nausea and cardiovascular issues, often associated with dopamine. Benserazide HCl improves the therapeutic profile of levodopa, allowing for lower doses and a more targeted approach to Parkinson’s treatment.