For research use only. Not for therapeutic Use.
Benzydamine is commonly used, in its hydrochloride form, as a local analgesic and anti-<wbr></wbr>inflammatory at oral and vaginal mucosal surfaces. Among its many effects, it locally suppresses histamine-<wbr></wbr>induced vasodilation and vascular permeability and blocks the production of TNF-<wbr></wbr>α by monocytes (IC<sub>50</sub> = 25 μM). Benzydamine is also abused by inhalation and gestation. This product is intended for forensic and research purposes.
| Catalog Number | R064994 |
| CAS Number | 642-72-8 |
| Synonyms | N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine |
| Molecular Formula | C19H23N3O |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine |
| InChI | InChI=1S/C19H23N3O/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16/h3-7,9-12H,8,13-15H2,1-2H3 |
| InChIKey | CNBGNNVCVSKAQZ-UHFFFAOYSA-N |
| SMILES | CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3 |
| Reference | 1.Huang, Y.S.,Hung, N.K.,Lee, M.S., et al. The effectiveness of benzydamine hydrochloride spraying on the endotracheal tube cuff or oral mucosa for postoperative sore throat. Anesthesia and Analgesia 111(4), 887-891 (2010). |
