Benzyl benzoate-d12

For research use only. Not for therapeutic Use.

  • CAT Number: I041668
  • CAS Number: 352431-26-6
  • Molecular Formula: C14D12O2
  • Molecular Weight: 224.32
  • Purity: ≥95%
Inquiry Now

Benzyl benzoate-d12 is the deuterium labeled Benzyl benzoate[1]. Benzyl benzoate (Benzoic acid benzyl ester) is a fragrance ingredient in cosmetic products. Benzyl benzoate can be used for the research of Scabies and Demodex-associated inflammatory skin conditions[2][3][4].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].


Catalog Number I041668
CAS Number 352431-26-6
Synonyms

[dideuterio-(2,3,4,5,6-pentadeuteriophenyl)methyl] 2,3,4,5,6-pentadeuteriobenzoate

Molecular Formula C14D12O2
Purity ≥95%
InChI InChI=1S/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H2/i1D,2D,3D,4D,5D,6D,7D,8D,9D,10D,11D2
InChIKey SESFRYSPDFLNCH-USINEXLCSA-N
SMILES C1=CC=C(C=C1)COC(=O)C2=CC=CC=C2
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]

[2]. Johnson W, et, al. Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate. Int J Toxicol. Nov/Dec 2017;36(3_suppl):5S-30S.
 [Content Brief]

[3]. Jacob S, et, al. Treatment of Demodex-associated inflammatory skin conditions: A systematic review. Dermatol Ther. 2019 Nov32(6):e13103.
 [Content Brief]

[4]. Dressler C, et, al. The Treatment of Scabies. Dtsch Arztebl Int. 2016 Nov 14113(45):757-762.
 [Content Brief]

Request a Quote