Benzyl-PEG4-acid

• CAT Number: I014165
• CAS Number: 127457-64-1
• Molecular Formula: C16H24O6
• Molecular Weight: 312.36
• Purity: ≥95%
• Synonyms: Benzyl-PEG4-acid;1-phenyl-2,5,8,11-tetraoxatetradecan-14-oic acid
• Target: PROTAC Linkers
• Solubility: Soluble in DMSO
• InChI: InChI=1S/C16H24O6/c17-16(18)6-7-19-8-9-20-10-11-21-12-13-22-14-15-4-2-1-3-5-15/h1-5H,6-14H2,(H,17,18)
• InChIKey: FGLPTVPWFDQWFM-UHFFFAOYSA-N
• SMILES: OC(CCOCCOCCOCCOCC1=CC=CC=C1)=O

Benzyl-PEG4-acid (Cat No.: I014165) is a polyethylene glycol (PEG)-based linker featuring a benzyl group and a terminal carboxylic acid. This versatile reagent is commonly used in drug conjugation, bioconjugation, and medicinal chemistry to enhance water solubility and bioavailability. The PEG4 spacer provides flexibility and reduces steric hindrance, making it ideal for linker design in targeted drug delivery, antibody-drug conjugates (ADCs), and click chemistry. Its applications span pharmaceutical research, peptide synthesis, and chemical modifications in biomedical studies.

Reference

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