Benzyl selenocyanate

• CAT Number: I045420
• CAS Number: 4671-93-6
• Molecular Formula: C8H7NSe
• Molecular Weight: 196.11
• Purity: ≥95%
• Synonyms: benzyl selenocyanate
• InChI: InChI=1S/C8H7NSe/c9-7-10-6-8-4-2-1-3-5-8/h1-5H,6H2
• InChIKey: WSKWDMOVMQKKQI-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C[Se]C#N

Benzyl selenocyanate is a chemopreventive agent for various chemically induced tumors in animal models at both the initiation and postinitiation stages. Benzyl selenocyanate is an inhibitor of DNA (cytosine-5)-methyltransferase (Mtase), with an with an IC50 of 8.4 µM[1].
Benzyl selenocyanate inhibits the activity of DNA (cytosine-5)-methyltransferase (Mtase) in a concentration-dependent manner[1].

Reference

[1]. E S Fiala, er al. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation. Carcinogenesis. 1998 Apr;19(4):597-604.
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