Bephenium hydroxynaphthoate

• CAT Number: I003402
• CAS Number: 3818-50-6
• Molecular Formula: C28H29NO4
• Molecular Weight: 443.53
• Purity: ≥95%
• Solubility: DMSO: ≥ 44 mg/mL
• Storage: Store at -20°C
• IUPAC Name: benzyl-dimethyl-(2-phenoxyethyl)azanium;3-carboxynaphthalen-2-olate
• InChI: InChI=1S/C17H22NO.C11H8O3/c1-18(2,15-16-9-5-3-6-10-16)13-14-19-17-11-7-4-8-12-17;12-10-6-8-4-2-1-3-7(8)5-9(10)11(13)14/h3-12H,13-15H2,1-2H3;1-6,12H,(H,13,14)/q+1;/p-1
• InChIKey: PMPQCPQAHTXCDK-UHFFFAOYSA-M
• SMILES: C[N+](C)(CCOC1=CC=CC=C1)CC2=CC=CC=C2.C1=CC=C2C=C(C(=CC2=C1)C(=O)O)[O-]

Bephenium hydroxynaphthoate（Cat No.:I003402）is an anthelmintic medication used to treat intestinal parasitic infections, particularly those caused by hookworms and roundworms. It works by targeting the parasite’s neuromuscular system, causing paralysis and allowing the body to expel the parasite naturally. Bephenium is known for its effectiveness in single-dose regimens, providing a convenient treatment option in areas with high prevalence of helminth infections. Its safety profile and targeted action make it suitable for broad use in deworming programs, aiding in the control of parasitic infections and promoting public health in endemic regions.

Reference

[1]. JAYEWARDENE G, et al. Bephenium hydroxynaphthoate in treatment of ascariasis. Br Med J. 1960 Jul 23;2(5194):268-71.
[2]. Charvet CL, et al. Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors. Invert Neurosci. 2012 Jun;12(1):43-51.
[3]. Charvet CL, et al. Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors. Invert Neurosci. 2012 Jun;12(1):43-51.