Bergapten

• CAT Number: A001019
• CAS Number: 484-20-8
• Molecular Formula: C12H8O4
• Molecular Weight: 216.19
• Purity: ≥95%
• Target: Autophagy
• Storage: -20°C
• IUPAC Name: 4-methoxyfuro[3,2-g]chromen-7-one
• InChI: InChI=1S/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,1H3
• InChIKey: BGEBZHIAGXMEMV-UHFFFAOYSA-N
• SMILES: COC1=C2C=CC(=O)OC2=CC3=C1C=CO3

Bergapten（Cat No.:A001019）, also known as 5-methoxypsoralen, is a naturally occurring furanocoumarin found in various citrus fruits, especially bergamot. It is widely studied for its photosensitizing properties, which are utilized in PUVA (psoralen and UVA) therapy for treating skin conditions like psoriasis and vitiligo. Bergapten interacts with DNA under UV light, inhibiting cellular proliferation and promoting apoptosis in hyperproliferative cells. Beyond dermatological applications, it has demonstrated anti-inflammatory, antioxidant, and anticancer properties, making it a versatile compound for research in therapeutic and medicinal chemistry.