For research use only. Not for therapeutic Use.
BET Bromodomain Inhibitor 1（Cat No.:I015512）is a small-molecule compound that selectively targets the bromodomain and extraterminal (BET) protein family, including BRD2, BRD3, BRD4, and BRDT. These proteins recognize acetylated lysine residues on histones and regulate transcription of genes controlling cell cycle progression, inflammation, and oncogenesis. By blocking BET bromodomains, this inhibitor suppresses expression of oncogenic drivers such as MYC, making it valuable in cancer biology and epigenetic research. BET Bromodomain Inhibitor 1 serves as a tool to dissect chromatin-mediated transcription and explore therapeutic strategies for cancer and inflammation.
| CAS Number | 2411226-02-1 |
| Synonyms | 6-[2-(2,4-difluorophenoxy)-5-(ethylsulfonylmethyl)pyridin-3-yl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-one |
| Molecular Formula | C22H19F2N3O4S |
| Purity | ≥95% |
| IUPAC Name | 6-[2-(2,4-difluorophenoxy)-5-(ethylsulfonylmethyl)pyridin-3-yl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-one |
| InChI | InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)12-14-9-16(18-8-13(2)20-21(28)25-6-7-27(18)20)22(26-11-14)31-19-5-4-15(23)10-17(19)24/h4-11H,3,12H2,1-2H3,(H,25,28) |
| InChIKey | UETQFSCWDMJWMM-UHFFFAOYSA-N |
| SMILES | CCS(=O)(=O)CC1=CC(=C(N=C1)OC2=C(C=C(C=C2)F)F)C3=CC(=C4N3C=CNC4=O)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
