beta-lactamase-IN-1

• CAT Number: I000344
• CAS Number: 1075237-97-6
• Molecular Formula: C11H13N3O4
• Molecular Weight: 251.24
• Purity: ≥95%
• Solubility: DMSO ≥ 32 mg/mL
• Storage: Store at -20°C
• IUPAC Name: 4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one
• InChI: InChI=1S/C11H13N3O4/c1-18-9-3-2-8-11(13-9)14(7(5-15)6-16)10(17)4-12-8/h2-4,7,15-16H,5-6H2,1H3
• InChIKey: VOAJCTMMHSBQGS-UHFFFAOYSA-N
• SMILES: COC1=NC2=C(C=C1)N=CC(=O)N2C(CO)CO

Beta-lactamase-IN-1（Cat No.:I000344）is a potent inhibitor of beta-lactamases, enzymes that confer resistance to beta-lactam antibiotics. It works by binding to the active site of the beta-lactamase enzyme, preventing it from hydrolyzing the beta-lactam ring structure in antibiotics. This inhibition restores the effectiveness of beta-lactam antibiotics against resistant bacteria. Beta-lactamase-IN-1 is utilized in research focused on overcoming antibiotic resistance, particularly in Gram-negative bacteria. It is a valuable tool in the development of new therapies and enhancing the efficacy of existing antibiotics in treating resistant infections.

Reference

[1]. PCT Int. Appl. (2016), WO 2016027249 A1 20160225.