Betahistine free base

• CAT Number: I004170
• CAS Number: 5638-76-6 (free base)
• Molecular Formula: C8H12N2
• Molecular Weight: 136.20
• Purity: ≥95%
• Synonyms: BRN0112294; BRN-0112294; BRN 0112294; beta-Histine; Betahistine; NSC 42617; PT 9 base; Serc base; Sinmenier (free base); Vasomotal. brand names Veserc, Serc, Hiserk, Betaserc, Vergo.;N-methyl-2-(pyridin-2-yl)ethan-1-amine
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term or -20 °C for long term
• IUPAC Name: N-methyl-2-pyridin-2-ylethanamine
• InChI: InChI=1S/C8H12N2/c1-9-7-5-8-4-2-3-6-10-8/h2-4,6,9H,5,7H2,1H3
• InChIKey: UUQMNUMQCIQDMZ-UHFFFAOYSA-N
• SMILES: CNCCC1=CC=CC=N1

Betahistine(CAT: I004170) is a histamine analog primarily used to treat Ménière’s disease and vertigo. It acts as an H1 receptor agonist and an H3 receptor antagonist, improving blood flow in the inner ear by causing vasodilation in the blood vessels of the labyrinth. This helps reduce the pressure caused by excess fluid, alleviating symptoms such as dizziness, tinnitus, and hearing loss. Betahistine free base also enhances the release of neurotransmitters like histamine, which plays a role in regulating balance and equilibrium. Its ability to manage vestibular disorders makes it a key therapeutic agent in otolaryngology.