Betahistine mesylate

For research use only. Not for therapeutic Use.

  • CAT Number: I023299
  • CAS Number: 54856-23-4
  • Molecular Formula: C10H20N2O6S2
  • Molecular Weight: 328.4
  • Purity: 98%
Inquiry Now

Betahistine mesylate(Cat No.:I023299) is a biochemical compound with potential therapeutic applications in the treatment of peripheral vertigo. Peripheral vertigo refers to a type of dizziness caused by dysfunction in the inner ear. Betahistine mesylate acts by enhancing blood flow to the inner ear and balancing the release of histamine, a neurotransmitter involved in regulating vestibular function.


Catalog Number I023299
CAS Number 54856-23-4
Synonyms

Betahistine mesilate; Betahistine mesylate; Extovyl; Meginalisk; Melopat; Merislon; Riptonin

Molecular Formula C10H20N2O6S2
Purity 98%
Target Neuronal Signaling
Solubility To be determined
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 2-(Ethylammonio)-N-methylpyridinium dimethanesulphonate
InChI InChI=1S/C8H12N2.2CH4O3S/c1-9-7-5-8-4-2-3-6-10-8;2*1-5(2,3)4/h2-4,6,9H,5,7H2,1H3;2*1H3,(H,2,3,4)
InChIKey ZBJJDYGJCNTNTH-UHFFFAOYSA-N
SMILES CNCCc1ccccn1.CS(=O)(=O)O.CS(=O)(=O)O
Reference

1. Murdin L, Hussain K, Schilder AG. Betahistine for symptoms of vertigo. Cochrane Database Syst Rev. 2016 Jun 21;2016(6):CD010696. doi: 10.1002/14651858.CD010696.pub2. PMID: 27327415; PMCID: PMC7388750.
2. Ramos Alcocer R, Ledezma Rodríguez JG, Navas Romero A, Cardenas Nuñez JL, Rodríguez Montoya V, Deschamps JJ, Liviac Ticse JA. Use of betahistine in the treatment of peripheral vertigo. Acta Otolaryngol. 2015;135(12):1205-11. doi: 10.3109/00016489.2015.1072873. Epub 2015 Aug 6. PMID: 26245698.
3. Adrion C, Fischer CS, Wagner J, Gürkov R, Mansmann U, Strupp M; BEMED Study Group. Efficacy and safety of betahistine treatment in patients with Meniere’s disease: primary results of a long term, multicentre, double blind, randomised, placebo controlled, dose defining trial (BEMED trial). BMJ. 2016 Jan 21;352:h6816. doi: 10.1136/bmj.h6816. PMID: 26797774; PMCID: PMC4721211.

Request a Quote