For research use only. Not for therapeutic Use.
Betamethasone(CAT: A001143) is a synthetic glucocorticoid receptor agonist with powerful anti-inflammatory and immunosuppressive properties, widely used in inflammation and dermatology research. By binding to glucocorticoid receptors, it modulates gene transcription to suppress pro-inflammatory cytokines, reduce leukocyte infiltration, and inhibit immune responses. This mechanism makes Betamethasone a valuable tool for studying conditions such as autoimmune diseases, allergic reactions, and skin disorders. Additionally, its role in regulating inflammation extends to investigations in respiratory, ophthalmic, and endocrine research, enabling the exploration of glucocorticoid pathways and therapeutic strategies for managing chronic inflammation and immune-mediated conditions.
Catalog Number | A001143 |
CAS Number | 378-44-9 |
Synonyms | NSC-39470, SCH-4831 |
Molecular Formula | C22H29FO5 |
Purity | ≥95% |
Target | Vitamin D Related/Nuclear Receptor |
Solubility | 19.6mg/mL in DMSO |
Storage | 3 years -20 ℃ |
IUPAC Name | (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
InChI | InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1 |
InChIKey | UREBDLICKHMUKA-DVTGEIKXSA-N |
SMILES | CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C |