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5593-20-4-Betamethasone Dipropionate Betamethasone Dipropionate

Betamethasone Dipropionate

For research use only. Not for therapeutic Use.

  • CAT Number: A000937
  • CAS Number: 5593-20-4
  • Molecular Formula: C28H37FO7
  • Molecular Weight: 504.59
  • Purity: ≥95%
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Research Areas: Glucocorticoid and Mineralocorticoid Pathway    

Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. It is applied as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other minor skin conditions such as eczema. Brand names include Alphatrex, Beta-Val, Diprolene, Diprolene AF, Diprosone, and Luxiq. Minor side-effects include dry skin and mild temporary stinging when applied.


Catalog Number A000937
CAS Number 5593-20-4
Synonyms

Diprosone; Diprolene; Diprolene AF; Diproderm; Maxivate

Molecular Formula C28H37FO7
Purity ≥95%
Storage -20°C
InChI 1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
InChIKey CIWBQSYVNNPZIQ-XYWKZLDCSA-N
SMILES CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC
Reference

1: Morita A, Muramatsu S, Kubo R, Ikumi K, Sagawa Y, Saito C, Torii K, Nishida E.
Low incidence of hypercalcemia following combined calcipotriol
hydrate/betamethasone dipropionate ointment treatment in Japanese patients with
severe psoriasis vulgaris. J Dermatolog Treat. 2017 Oct 27:1-16. doi:
10.1080/09546634.2017.1398394. [Epub ahead of print] PubMed PMID: 29076379.
<br>

2: Patel NU, Felix K, Reimer D, Feldman SR. Calcipotriene/betamethasone
dipropionate for the treatment of psoriasis vulgaris: an evidence-based review.
Clin Cosmet Investig Dermatol. 2017 Sep 29;10:385-391. doi: 10.2147/CCID.S131727.
eCollection 2017. Review. PubMed PMID: 29033598; PubMed Central PMCID:
PMC5628677.

<br>
3: Hashim PW, Nia JK, Terrano D, Goldenberg G, Kircik LH. A Comparative Study to
Evaluate Epidermal Barrier Integrity of Psoriasis Patients Treated With
Calcipotriene/Betamethasone Topical Suspension Versus Betamethasone Dipropionate
0.05% Lotion. J Drugs Dermatol. 2017 Aug 1;16(8):747-752. PubMed PMID: 28809989.

<br>
4: R&#248;pke M, Bulai Livideanu C, Kaldate R, Snel A, Paul C. Changes in
interleukin-17A, macrophage-derived chemokine and adiponectin following treatment
of psoriasis with calcipotriol plus betamethasone dipropionate aerosol foam:
results from the PSO-ABLE study. Br J Dermatol. 2017 Jul 19. doi:
10.1111/bjd.15814. [Epub ahead of print] PubMed PMID: 28722136.
<br>

5: Frieder J, Kivelevitch D, Menter A. Calcipotriene betamethasone dipropionate
aerosol foam in the treatment of plaque psoriasis: a review of the literature.
Ther Deliv. 2017 Aug;8(9):737-746. doi: 10.4155/tde-2017-0058. Epub 2017 Jun 29.
PubMed PMID: 28659016.

<br>
6: Takeichi T, Tsukamoto K, Okuno Y, Kojima D, Kono M, Suga Y, Akiyama M. A
combination of low-dose systemic etretinate and topical
calcipotriol/betamethasone dipropionate treatment for hyperkeratosis and itching
in Olmsted syndrome associated with a TRPV3 mutation. J Dermatol Sci. 2017
Oct;88(1):144-146. doi: 10.1016/j.jdermsci.2017.05.012. Epub 2017 May 29. PubMed
PMID: 28587736.

<br>
7: Asche CV, Kim M, Feldman SR, Zografos P, Lu M. Budget impact model in
moderate-to-severe psoriasis vulgaris assessing effects of calcipotriene and
betamethasone dipropionate foam on per-patient standard of care costs. J Med
Econ. 2017 Sep;20(9):1000-1006. doi: 10.1080/13696998.2017.1339279. Epub 2017 Jun
19. PubMed PMID: 28581873.
<br>

8: Paul C, Leonardi C, Menter A, Reich K, Gold LS, Warren RB, M&#248;ller A, Lebwohl
M. Erratum to: Calcipotriol Plus Betamethasone Dipropionate Aerosol Foam in
Patients with Moderate-to-Severe Psoriasis: Sub-Group Analysis of the PSO-ABLE
Study. Am J Clin Dermatol. 2017 Aug;18(4):591. doi: 10.1007/s40257-017-0295-8.
PubMed PMID: 28540589.
<br>

9: Menter A, Gold LS, Koo J, Villumsen J, Rosén M, Lebwohl M. Fixed-Combination
Calcipotriene Plus Betamethasone Dipropionate Aerosol Foam Is Well Tolerated in
Patients with Psoriasis Vulgaris: Pooled Data from Three Randomized Controlled
Studies. Skinmed. 2017 Apr 1;15(2):119-124. eCollection 2017. PubMed PMID:
28528605.
<br>

10: Paul C, Leonardi C, Menter A, Reich K, Gold LS, Warren RB, M&#248;ller A, Lebwohl
M. Calcipotriol Plus Betamethasone Dipropionate Aerosol Foam in Patients with
Moderate-to-Severe Psoriasis: Sub-Group Analysis of the PSO-ABLE Study. Am J Clin
Dermatol. 2017 Jun;18(3):405-411. doi: 10.1007/s40257-017-0258-0. Erratum in: Am
J Clin Dermatol. 2017 May 24;:. PubMed PMID: 28236223; PubMed Central PMCID:
PMC5422452.

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