For research use only. Not for therapeutic Use.
Betonicine(cas 515-25-3​) is ​Alkaloid, extracted from Achillea millefolium (Compositae Fam.)
It has hemostatic property. It is an inhibitor of bacterial signaling molecules (quorum-sensing inhibitor), which allows the transmission of resistance between bacteria. It is also an adjuvant to anti-infective treatments.<br> It possesses anti-inflammatory activity.
| Catalog Number | T000050 |
| CAS Number | 515-25-3 |
| Synonyms | (2S,4S)-4-hydroxy-1,1-dimethylpyrrolidin-1-ium-2-carboxylate |
| Molecular Formula | C7H13NO3 |
| Purity | ≥95% |
| Solubility | Water, hot alcohol |
| Storage | Stable in dry state, store at +4°C, in dark place. Solution for use in vitro: 10-7 M-10-5 M; dose for one experiment in vivo: 2-7 mg/kg (i.v.). |
| IUPAC Name | (2S,4R)-4-hydroxy-1,1-dimethylpyrrolidin-1-ium-2-carboxylate |
| InChI | InChI=1S/C7H13NO3/c1-8(2)4-5(9)3-6(8)7(10)11/h5-6,9H,3-4H2,1-2H3/t5-,6+/m1/s1 |
| InChIKey | MUNWAHDYFVYIKH-RITPCOANSA-N |
| SMILES | C[N+]1(CC(CC1C(=O)[O-])O)C |
| Reference | – Hai Liu, Kyong Koh, Jung Kim, Youngwan Seo, Sunghoon Park. The Effects of Betonicine, Floridoside, and Isethionic Acid from the Red Alga Ahnfeltiopsis flabelliformis on Quorum-Sensing ActivitY. Biotechnology and Bioprocess Engineering 2008, 13: 458-463<br /> |
