Betulinaldehyde

• CAT Number: I001218
• CAS Number: 13159-28-9
• Molecular Formula: C30H48O2
• Molecular Weight: 440.70
• Purity: ≥95%
• Target: Bacterial
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbaldehyde
• InChI: InChI=1S/C30H48O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h18,20-25,32H,1,8-17H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1
• InChIKey: FELCJAPFJOPHSD-ROUWMTJPSA-N
• SMILES: CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C=O

Betulinaldehyde（Cat No.:I001218）, also known as betulinic aldehyde, is a natural compound found in the bark of birch trees and other plants. It is a pentacyclic triterpenoid with potential therapeutic applications, including antitumor, anti-inflammatory, and antiviral properties. Betulinaldehyde has been shown to inhibit the growth of several cancer cell lines by inducing apoptosis and suppressing angiogenesis. It also exhibits antiviral activity against a variety of viruses, including HIV and herpes simplex virus. Betulinaldehyde is often used as a precursor for the synthesis of betulinic acid, a derivative with enhanced pharmacological activity.

Reference

[1]. Chung PY, et al. Identification, by gene expression profiling analysis, of novel gene targets in Staphylococcus aureus treated with betulinaldehyde. Res Microbiol. 2013 May;164(4):319-26.

[2]. Chung PY, et al. Transcriptional profiles of the response of methicillin-resistant Staphylococcus aureus to pentacyclic triterpenoids. PLoS One. 2013;8(2):e56687.