For research use only. Not for therapeutic Use.
BGB-8035 is an orally active, highly selective inhibitor of Bruton’s tyrosine kinase (BTK) with IC50 values of 1.1 nM for BTK, respectively. BGB-8035 exhibits antitumor and anti-arthritis activity and displays potential for its use in research of B-cell malignancies and autoimmune diseases.
Catalog Number | I047189 |
CAS Number | 2283349-24-4 |
Molecular Formula | C24H31N5O4 |
Purity | ≥95% |
Reference | [1] Guo Y, et al. J Med Chem. 2023 Mar 23;66(6):4025-4044. |