For research use only. Not for therapeutic Use.
BI-10N is a potent antagonist of Interleukin-2 inducible T-cell kinase (ITK).
Catalog Number | I023344 |
CAS Number | 1149753-56-9 |
Synonyms | BI-10N; BI-10-N; BI10N; BI 10N; BI 10 N; |
Molecular Formula | C26H34N6O2S |
Purity | 98% |
Target | Itk |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | N-[1-(2-Hydroxy-2-methylpropyl)-5-[[[(1S)-1,2,2-trimethylpropyl]amino]methyl]-1H-benzimidazol-2-yl]-5-(1H-pyrazol-4-yl)-2-thiophenecarboxamide |
InChI | InChI=1S/C26H34N6O2S/c1-16(25(2,3)4)27-12-17-7-8-20-19(11-17)30-24(32(20)15-26(5,6)34)31-23(33)22-10-9-21(35-22)18-13-28-29-14-18/h7-11,13-14,16,27,34H,12,15H2,1-6H3,(H,28,29)(H,30,31,33)/t16-/m0/s1 |
InChIKey | MUAICZWSFWUFNA-INIZCTEOSA-N |
SMILES | O=C(C1=CC=C(C2=CNN=C2)S1)NC3=NC4=CC(CN[C@@H](C)C(C)(C)C)=CC=C4N3CC(C)(O)C |