Biapenem

• CAT Number: A000549
• CAS Number: 120410-24-4
• Molecular Formula: C15H18N4O4S
• Molecular Weight: 350.39
• Purity: 95%
• Synonyms: 120410-24-4; Omegacin; Biapenern; L-627; Biapenem [USAN:INN]
• Target: Beta-lactamase
• Solubility: Limited solubility
• Appearance: White to Yellow Solid
• Storage: -20°C
• Analysis method: HPLC
• IUPAC Name: (4R,5S,6S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
• InChI: InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1
• InChIKey: MRMBZHPJVKCOMA-YJFSRANCSA-N
• SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1SC3CN4C=NC=[N+]4C3)C(=O)[O-])[C@@H](C)O

Biapenem（Cat No.:A000549）is a carbapenem antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria, including resistant strains. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death. Biapenem is effective for treating complicated infections, including respiratory, intra-abdominal, and urinary tract infections, often used in severe or hospital-acquired cases. Known for its stability against beta-lactamase enzymes, it is particularly useful against multidrug-resistant organisms. Its favorable pharmacokinetic profile and low toxicity make it a reliable option in serious bacterial infections.