Bicyclo[1.1.1]pentane-1,3-dicarboxamide

• CAT Number: L013390
• CAS Number: 1379318-53-2
• Molecular Formula: C7H10N2O2
• Molecular Weight: 154.17
• Purity: ≥95%
• IUPAC Name: bicyclo[1.1.1]pentane-1,3-dicarboxamide
• InChI: InChI=1S/C7H10N2O2/c8-4(10)6-1-7(2-6,3-6)5(9)11/h1-3H2,(H2,8,10)(H2,9,11)
• InChIKey: PYHITRSVNYVALL-UHFFFAOYSA-N

Bicyclo[1.1.1]pentane-1,3-dicarboxamide(CAT: L013390) is a derivative of the bicyclo[1.1.1]pentane (BCP) scaffold, featuring two amide groups at the 1 and 3 positions. This compound is particularly useful in medicinal chemistry as a rigid, sp³-rich bioisostere of benzene and other aromatic rings, offering enhanced metabolic stability and solubility. The BCP structure provides a unique three-dimensional geometry, which helps improve the pharmacokinetic and physicochemical properties of drug candidates. Bicyclo[1.1.1]pentane-1,3-dicarboxamide is widely employed as a building block in drug design, especially for developing compounds with better receptor binding profiles and reduced off-target effects.