For research use only. Not for therapeutic Use.
Bifeprunox, also known as DU-127090, is a partial dopamine and serotonin agonist potentially for the treatment of schizophrenia. Bifeprunox influences nicotine-seeking behaviour in response to drug-associated stimuli in rats. Bifeprunox suppresses in viv
| Catalog Number | I004245 |
| CAS Number | 350992-13-1 (mesylate) |
| Synonyms | Bifeprunox; Bifeprunox Mesylate; DU-127090; DU 127090; DU127090.;7-(4-(Biphenyl-3-ylmethyl)piperazin-1-yl)benzoxazol-2(3H)-one methanesulfonate |
| Molecular Formula | C25H27N3O5S |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| IUPAC Name | methanesulfonic acid;7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one |
| InChI | InChI=1S/C24H23N3O2.CH4O3S/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19;1-5(2,3)4/h1-11,16H,12-15,17H2,(H,25,28);1H3,(H,2,3,4) |
| InChIKey | ONWKHSGOYGLGPO-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)O.C1CN(CCN1CC2=CC=CC(=C2)C3=CC=CC=C3)C4=CC=CC5=C4OC(=O)N5 |
| Reference | </br> 1: Chattopadhyay A, Frey S, Green G, Harkness A, McDermott A, Yates A. Bifeprunox vs Placebo for Schizophrenia. Schizophr Bull. 2016 Jul;42(4):881-2. doi: 10.1093/schbul/sbw048. Epub 2016 May 6. PubMed PMID: 27153863; PubMed Central PMCID: PMC490306 |
