For research use only. Not for therapeutic Use.
BigLEN(mouse) is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ∼0.5 nM. BigLEN(mouse) can be used to regulate responses associated with food intake and metabolism[1][2].
| Catalog Number | I008227 |
| CAS Number | 501036-69-7 |
| Molecular Formula | C78H130N24O22 |
| Purity | ≥95% |
| Reference | [1]. Gomes I, et, al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16211-6. [2]. Mack SM, et, al. Neuropeptide PEN and Its Receptor GPR83: Distribution, Signaling, and Regulation. ACS Chem Neurosci. 2019 Apr 17;10(4):1884-1891. |
