Bintrafusp alfa

• CAT Number: I042156
• CAS Number: 1918149-01-5
• Purity: ≥95%

Bintrafusp alfa（Cat No.:I042156）is an investigational bifunctional fusion protein that targets two immune checkpoint receptors: PD-L1 (programmed death-ligand 1) and TGF-β (transforming growth factor-beta). PD-L1 is commonly expressed on cancer cells, allowing them to evade immune detection, while TGF-β suppresses immune responses and promotes tumor growth. Bintrafusp alfa combines the blockade of both these pathways to enhance the immune system’s ability to recognize and destroy cancer cells. It is being studied in clinical trials for its potential to treat various cancers, including solid tumors, with a focus on improving patient outcomes.