BioGEE

• CAT Number: C000401
• CAS Number: 502635-76-9
• Molecular Formula: C₂₄H₃₉N₅O₈S₂
• Molecular Weight: 589.73
• Purity: ≥95%
• Synonyms: N-[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-?-glutamyl-L-cysteinyl-glycine Diethyl Ester
• IUPAC Name: ethyl (2S)-2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-5-[[(2R)-1-[(2-ethoxy-2-oxoethyl)amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoate
• InChI: InChI=1S/C24H39N5O8S2/c1-3-36-20(32)11-25-22(33)15(12-38)27-19(31)10-9-14(23(34)37-4-2)26-18(30)8-6-5-7-17-21-16(13-39-17)28-24(35)29-21/h14-17,21,38H,3-13H2,1-2H3,(H,25,33)(H,26,30)(H,27,31)(H2,28,29,35)/t14-,15-,16-,17-,21-/m0/s1
• InChIKey: VGOHDJNDRRARHP-QHXHSKPESA-N
• SMILES: CCOC(=O)CNC(=O)C(CS)NC(=O)CCC(C(=O)OCC)NC(=O)CCCCC1C2C(CS1)NC(=O)N2

BioGEE (Biotinylated Glutathione Ethyl Ester)（Cat No.:C000401）is a cell-permeable compound used in biochemical and cell biology research to study glutathione-related processes. This biotinylated derivative of glutathione is designed to cross cell membranes and participate in intracellular redox reactions. Once inside the cell, BioGEE can be used to label and track glutathione-associated proteins, providing insights into oxidative stress, detoxification, and cellular defense mechanisms. Its biotin tag allows for easy detection and isolation using streptavidin-based assays, making BioGEE an essential tool in redox biology and proteomics research.

Reference

Sullivan, D. M., et al.: Methods Enzymol., 353, 101-113 (2002);