Biotin-labeled ODN 1826 sodium

• CAT Number: I041009
• Purity: ≥95%

Biotin-labeled ODN 1826 sodium(CAT: I041009) is a synthetic oligodeoxynucleotide (ODN) that mimics the immunostimulatory properties of bacterial DNA, specifically through its CpG motifs. This compound is conjugated with biotin to facilitate easy detection and capture in various assay formats, including ELISA, western blot, and flow cytometry. Biotin-labeled ODN 1826 sodium activates Toll-like receptor 9 (TLR9) on immune cells, promoting the release of pro-inflammatory cytokines and enhancing immune responses. It is particularly useful in studying the role of TLR9 in autoimmune diseases, infection models, and cancer immunotherapy, providing a powerful tool for exploring innate immune activation and the development of immunomodulatory therapies.