Biotin-PEG2-NH-Boc

• CAT Number: I014192
• CAS Number: 175885-18-4
• Molecular Formula: C21H38N4O6S
• Molecular Weight: 474.62
• Purity: ≥95%
• Synonyms: Biotin-PEG2-NH-Boc;tert-butyl (2-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)ethyl)carbamate
• Target: PROTAC Linkers
• Solubility: Soluble in DMSO
• InChI: InChI=1S/C21H38N4O6S/c1-21(2,3)31-20(28)23-9-11-30-13-12-29-10-8-22-17(26)7-5-4-6-16-18-15(14-32-16)24-19(27)25-18/h15-16,18H,4-14H2,1-3H3,(H,22,26)(H,23,28)(H2,24,25,27)/t15-,16-,18-/m0/s1
• InChIKey: GCMGCUOONLVCAK-BQFCYCMXSA-N
• SMILES: O=C1N[C@@]2([H])CS[C@@H](CCCCC(NCCOCCOCCNC(OC(C)(C)C)=O)=O)[C@@]2([H])N1

Biotin-PEG2-NH-Boc(CAT: I014192) is a biotin PEG linker. This compound consists of a biotin group, a PEG chain, and a Boc-protected amino group. Biotin-PEG2-NH-Boc is commonly used in the field of bioconjugation and drug development, particularly in the creation of antibody-drug conjugates (ADCs). The biotin group allows for specific binding to avidin or streptavidin, enabling targeted delivery of the conjugate to biotin-binding proteins or cells. The PEG chain provides flexibility and solubility, and the Boc protection can be removed to expose the amino group to further chemical reactions.

Reference

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