For research use only. Not for therapeutic Use.
Amine-PEG3-Biotin (Cat No.: I014196) is a signal amplification marker that features a biotin group along with a terminal primary amino group. This compound serves a critical role in various biological and biochemical applications, particularly in signal amplification techniques. Its dual functionality allows for the selective binding of biotin to streptavidin or avidin, enabling the detection and visualization of target molecules with enhanced sensitivity. Researchers frequently utilize Amine-PEG3-Biotin in assays, labeling, and detection processes where signal amplification is essential, making it a valuable tool in molecular biology and biotechnology research. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.
| Catalog Number | I014196 |
| CAS Number | 359860-27-8 |
| Synonyms | Biotin-PEG3-amine;N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
| Molecular Formula | C18H34N4O5S |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]pentanamide |
| InChI | InChI=1S/C18H34N4O5S/c19-5-7-25-9-11-27-12-10-26-8-6-20-16(23)4-2-1-3-15-17-14(13-28-15)21-18(24)22-17/h14-15,17H,1-13,19H2,(H,20,23)(H2,21,22,24)/t14-,15-,17-/m0/s1 |
| InChIKey | KIJSBKNJFAUJFV-ZOBUZTSGSA-N |
| SMILES | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCN)NC(=O)N2 |
| Reference | </br>1: Deng CY, Long YY, Liu S, Chen ZB, Li C. [Construction of biotin-modified polymeric micelles for pancreatic cancer targeted photodynamic therapy]. Yao Xue Xue Bao. 2015 Aug;50(8):1038-44. Chinese. PubMed PMID: 26669006.</br>2: Zhu W, Song Z, Wei P, Meng N, Teng F, Yang F, Liu N, Feng R. Y-shaped biotin-conjugated poly (ethylene glycol)-poly (epsilon-caprolactone) copolymer for the targeted delivery of curcumin. J Colloid Interface Sci. 2015 Apr 1;443:1-7. doi: 10.1016/j.jcis.2014.11.073. Epub 2014 Dec 6. PubMed PMID: 25526295.</br>3: Ke S, Wright JC, Kwon GS. Avidin-biotin-PEG-CPA complexes as potential EPR-directed therapeutic protein carriers: preparation and characterization. Bioconjug Chem. 2007 Sep-Oct;18(5):1644-50. Epub 2007 Aug 18. PubMed PMID: 17705554.</br>4: Kaiser K, Marek M, Haselgrübler T, Schindler H, Gruber HJ. Basic studies on heterobifunctional biotin-PEG conjugates with a 3-(4-pyridyldithio)propionyl marker on the second terminus. Bioconjug Chem. 1997 Jul-Aug;8(4):545-51. PubMed PMID: 9258454.</br></br> |
