Biotin-PEG4-acid

• CAT Number: I014204
• CAS Number: 721431-18-1
• Molecular Formula: C21H37N3O8S
• Molecular Weight: 491.6
• Purity: ≥95%
• Synonyms: Biotin-PEG4-acid;17-oxo-21-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13-tetraoxa-16-azahenicosanoic acid
• Solubility: Soluble in DMSO
• InChI: InChI=1S/C21H37N3O8S/c25-18(4-2-1-3-17-20-16(15-33-17)23-21(28)24-20)22-6-8-30-10-12-32-14-13-31-11-9-29-7-5-19(26)27/h16-17,20H,1-15H2,(H,22,25)(H,26,27)(H2,23,24,28)/t16-,17-,20-/m0/s1
• InChIKey: GYOXFFWLRKVJJX-ZWOKBUDYSA-N
• SMILES: O=C1N[C@@]2([H])CS[C@@H](CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)[C@@]2([H])N1

Biotin-PEG4-acid (CAT: I014204) is a heterobiofunctional biotin derivative with a PEG spacer arm consisting of four ethylene glycol units. The presence of a carboxylic acid group enhances water solubility, facilitating its conjugation to biotinylated molecules. This linker offers versatility in applications such as the development of antibody-drug conjugates (ADCs).

Reference

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