Biotin-PEG4-methyltetrazine

• CAT Number: I014209
• CAS Number: 1835759-81-3
• Molecular Formula: C27H39N7O6S
• Molecular Weight: 589.71
• Purity: ≥95%
• Synonyms: Biotin-PEG4-methyltetrazine;N-(2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
• Target: PROTAC Linkers
• Solubility: Soluble in DMSO
• IUPAC Name: 5-[(3aR,4R,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide
• InChI: InChI=1S/C27H39N7O6S/c1-19-31-33-26(34-32-19)20-6-8-21(9-7-20)40-17-16-39-15-14-38-13-12-37-11-10-28-24(35)5-3-2-4-23-25-22(18-41-23)29-27(36)30-25/h6-9,22-23,25H,2-5,10-18H2,1H3,(H,28,35)(H2,29,30,36)/t22-,23-,25-/m1/s1
• InChIKey: FTGDGKKLLGMCLG-VDKIKQQVSA-N
• SMILES: CC1=NN=C(N=N1)C2=CC=C(C=C2)OCCOCCOCCOCCNC(=O)CCCC[C@@H]3[C@H]4[C@@H](CS3)NC(=O)N4

Biotin-PEG4-methyltetrazine（Cat No.:I014209）is a bioconjugate compound used in molecular biology and targeted drug delivery applications. It consists of biotin, a vitamin known for its ability to bind tightly to streptavidin, linked to a polyethylene glycol (PEG4) chain for enhanced solubility and stability. The methyltetrazine group enables the compound to undergo bioorthogonal reactions, allowing for selective conjugation with other molecules, such as antibodies or drugs, in a process known as “click chemistry.” This compound is commonly used in drug-targeting, imaging, and biomarker detection, facilitating precise delivery of therapeutic agents or probes.

Reference

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