Birinapant

• CAT Number: I001041
• CAS Number: 1260251-31-7
• Molecular Formula: C₄₂H₅₆F₂N₈O₆
• Molecular Weight: 806.94
• Purity: ≥95%
• Synonyms: TL32711; (2S,2/’S)-N,N/’-((2S,2/’S)-((3S,3/’S,5R,5/’R)-5,5/’-((6,6/’-difluoro-1H,1/’H-[2,2/’-biindole]-3,3/’-diyl)bis(methylene))bis(3-hydroxypyrrolidine-5,1-diyl))bis(1-oxobutane-2,1-diyl))bis(2-(methylamino)propanamide)
• Target: Anti-infection
• Solubility: DMSO: ≥ 40 mg/mL
• Storage: 3 years -20C powder
• IC50: 45 nM (Kd, XIAP); <1 nM (Kd cIAP1)
• InChI: InChI=1S/C42H56F2N8O6/c1-7-33(49-39(55)21(3)45-5)41(57)51-19-27(53)15-25(51)17-31-29-11-9-23(43)13-35(29)47-37(31)38-32(30-12-10-24(44)14-36(30)48-38)18-26-16-28(54)20-52(26)42(58)34(8-2)50-40(56)22(4)46-6/h9-14,21-22,25-28,33-34,45-48,53-54H,7-8,15-20H2,
• InChIKey: PKWRMUKBEYJEIX-DXXQBUJASA-N
• SMILES: CCC(C(=O)N1CC(CC1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)CC6CC(CN6C(=O)C(CC)NC(=O)C(C)NC)O)O)NC(=O)C(C)NC

Birinapant(CAT: I001041) is a small molecule inhibitor that selectively targets inhibitors of apoptosis proteins (IAPs), which are a family of proteins that regulate programmed cell death. By inhibiting the activity of IAPs, birinapant can promote the induction of apoptosis, or programmed cell death, in cancer cells. This mechanism of action makes birinapant a potential therapeutic agent for the treatment of various types of cancer. In preclinical studies, birinapant has shown promising results, and it is currently being evaluated in clinical trials for its safety and efficacy in cancer therapy.