Bis(2-chloroethyl)amine Hydrochloride

• CAT Number: R055676
• CAS Number: 821-48-7
• Molecular Formula: C4H10Cl3N
• Molecular Weight: 178.48
• Purity: ≥95%
• Synonyms: 2-Chloro-N-(2-chloroethyl)ethanamine Hydrochloride; USP Cyclophosphamide Related Compound A
• Storage: Store at 4°C
• IUPAC Name: 2-chloro-N-(2-chloroethyl)ethanamine;hydrochloride
• InChI: InChI=1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H
• InChIKey: YMDZDFSUDFLGMX-UHFFFAOYSA-N
• SMILES: C(CCl)NCCCl.Cl

Bis(2-chloroethyl)amine hydrochloride（Cat No.:R055676）, commonly known as mechlorethamine hydrochloride, is a nitrogen mustard alkylating agent used primarily in chemotherapy. As one of the earliest chemotherapy agents, it functions by cross-linking the strands of DNA in cancer cells, inhibiting their ability to replicate and ultimately causing cell death. It is specifically effective against rapidly dividing cells, making it useful in treating various types of cancer, including Hodgkin’s disease, lymphoma, and leukemia. Despite its efficacy, the use of mechlorethamine is limited by its potential to cause severe side effects, such as immunosuppression and mucosal damage.