Bis-NH2-C1-PEG3

• CAT Number: I018605
• CAS Number: 4246-51-9
• Molecular Formula: C₁₀H₂₄N₂O₃
• Molecular Weight: 220.31
• Purity: ≥95%
• Target: PROTAC Linkers
• IUPAC Name: 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine
• InChI: InChI=1S/C10H24N2O3/c11-3-1-5-13-7-9-15-10-8-14-6-2-4-12/h1-12H2
• InChIKey: JCEZOHLWDIONSP-UHFFFAOYSA-N
• SMILES: C(CN)COCCOCCOCCCN

Bis-NH2-C1-PEG3 (Cat No.:I018605) is a PEG-based PROTAC linker that can be used to synthesize PROTACs, has a certain basicity, can be used as an organic intermediate, can be produced from acrylonitrile and diethylene glycol through two prepared in one step reaction.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.