For research use only. Not for therapeutic Use.
Bis-PEG3-acid(CAT: I014248), with the chemical name 2,2′-[3,6-dioxaoctane-1,8-diylbis(oxy)]diacetic acid, is a PEG (polyethylene glycol) derivative that consists of two terminal carboxylic acid groups. This compound can serve as a linker or building block in various chemical and biochemical applications, including the synthesis of drug delivery systems, biomaterials, and conjugates. Its structure allows for potential conjugation to other molecules or surfaces, enabling the creation of functionalized compounds with specific properties for diverse research and industrial purposes.
| Catalog Number | I014248 |
| CAS Number | 96517-92-9 |
| Synonyms | Bis-PEG3-acid;3,3′-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid |
| Molecular Formula | C10H18O7 |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Solubility | Soluble in DMSO |
| InChI | InChI=1S/C10H18O7/c11-9(12)1-3-15-5-7-17-8-6-16-4-2-10(13)14/h1-8H2,(H,11,12)(H,13,14) |
| InChIKey | WFLUHYUKINZPNZ-UHFFFAOYSA-N |
| SMILES | OC(CCOCCOCCOCCC(O)=O)=O |
| Reference | </br>1: Bonache MA, Alaimo A, Malo C, Millet O, Villarroel A, González-Muñiz R. Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding. Org Biomol Chem. 2014 Nov 28;12(44):8877-87. doi: 10.1039/c4ob01338g. PubMed PMID: 25264745.</br>2: Aroua S, Schweizer WB, Yamakoshi Y. C60 pyrrolidine bis-carboxylic acid derivative as a versatile precursor for biocompatible fullerenes. Org Lett. 2014 Mar 21;16(6):1688-91. doi: 10.1021/ol500363r. Epub 2014 Mar 7. PubMed PMID: 24606113.</br>3: Kakkar D, Tiwari AK, Chuttani K, Khanna A, Datta A, Singh H, Mishra AK. Design, synthesis, and antimycobacterial property of PEG-bis(INH) conjugates. Chem Biol Drug Des. 2012 Aug;80(2):245-53. doi: 10.1111/j.1747-0285.2012.01394.x. Epub 2012 May 30. PubMed PMID: 22515497.</br></br> |
