For research use only. Not for therapeutic Use.
Bis-PEG9-acid (Cat No.:I014258) is a PROTAClinker, belonging to the PEG class. Bis-PEG9-acid can be used to synthesize a series of PROTChemicalbookAC molecules. Bis-PEG9-acid is a cleavable ADClinker for the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | I014258 |
| CAS Number | 1268488-70-5 |
| Synonyms | Bis-PEG9-acid;4,7,10,13,16,19,22,25,28-nonaoxahentriacontanedioic acid |
| Molecular Formula | C22H42O13 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 2-8°C |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| InChI | InChI=1S/C22H42O13/c23-21(24)1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-20-18-34-16-14-32-12-10-30-8-6-28-4-2-22(25)26/h1-20H2,(H,23,24)(H,25,26) |
| InChIKey | MZPXCHJGEDEJHQ-UHFFFAOYSA-N |
| SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O |
| Reference | </br>1: Bonache MA, Alaimo A, Malo C, Millet O, Villarroel A, González-Muñiz R. Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding. Org Biomol Chem. 2014 Nov 28;12(44):8877-87. doi: 10.1039/c4ob01338g. PubMed PMID: 25264745.</br>2: Aroua S, Schweizer WB, Yamakoshi Y. C60 pyrrolidine bis-carboxylic acid derivative as a versatile precursor for biocompatible fullerenes. Org Lett. 2014 Mar 21;16(6):1688-91. doi: 10.1021/ol500363r. Epub 2014 Mar 7. PubMed PMID: 24606113.</br>3: Kakkar D, Tiwari AK, Chuttani K, Khanna A, Datta A, Singh H, Mishra AK. Design, synthesis, and antimycobacterial property of PEG-bis(INH) conjugates. Chem Biol Drug Des. 2012 Aug;80(2):245-53. doi: 10.1111/j.1747-0285.2012.01394.x. Epub 2012 May 30. PubMed PMID: 22515497.</br></br> |
